Miguel Pajares, a Spanish missionary priest who contracted the Ebola virus in west Africa, has died in a hospital in Madrid, reports the Associated Press.
Pajares' death comes amid intense debate surrounding experimental treatment for the virus.
On Sunday, the Spanish government said that Pajares — the first European infected in this outbreak — would be treated with the untested ZMapp serum, Reuters reported.
Following his death, Madrid's Carlos III Hospital have not confirmed that he had been treated with the drug, according to AP.
The treatment, which hasn't been tested on humans, has been given to two Americans who contracted the virus.
Earlier, the Liberian presidency said the United States had approved a request to send sample doses of ZMapp to treat local doctors, according to Al Jazeera.
The Liberian government announced the news via a statement on the presidency's website. The drug will be used to treat Liberian doctors who contracted the disease.
Liberian information minister Lewis Brown told Reuters that it was unclear how many doses of the drug had been sent, but they could be in the country's capital, Monrovia, within the next 48 hours, Al Jazeera says.
However, Mapp Pharmaceutical — the California-based firm behind ZMapp — released a statement on Monday saying its supply of the treatment had been exhausted.
Meanwhile, the World Health Organization released a statement regarding the ethical considerations regarding the use of untested Ebola treatments.
After convening yesterday, the WHO decided that the unregistered treatments were ethical in the particular circumstances of this outbreak, providing certain conditions are met.
So far, 1,848 people have been infected with the Ebola virus during the current outbreak, and 1,013 people have died.
Click here for a further breakdown of Ebola cases across west Africa.